Human milk glycosaminoglycans: the state of the art and future perspectives

نویسندگان

  • Giovanni Valentino Coppa
  • Orazio Gabrielli
  • Enrico Bertino
  • Lucia Zampini
  • Tiziana Galeazzi
  • Lucia Padella
  • Lucia Santoro
  • Rita Lucia Marchesiello
  • Fabio Galeotti
  • Francesca Maccari
  • Nicola Volpi
چکیده

Recently, a complete characterization and detailed evaluation of the glycosaminoglycans of human milk were performed. The total glycosaminoglycans content in milk from healthy mothers having delivered term or preterm newborns showed a constant pattern which was essentially composed of two main polysaccharides: chondroitin sulfate (60-70%) and heparin (30-40%). Moreover, considerable variations of glycosaminoglycans concentration were found during the first month of lactation, the highest values being present in colostrum compared to mature milk. Metabolism and potential biological functions of human milk glycosaminoglycans are hypothesized and future studies are encouraged.

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عنوان ژورنال:

دوره 39  شماره 

صفحات  -

تاریخ انتشار 2013